ATXA Therapeutics have published a new paper detailing results of its lead drug candidate NTP42 in a preclinical model of pulmonary arterial hypertension (PAH). These key findings show how NTP42 and antagonism of the thromboxane signalling pathway have a relevant role in alleviating the pathophysiology of PAH, representing a novel therapeutic target with marked benefits over existing standard-of-care therapies. The manuscript, entitled NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension, was recently accepted for publication in BMC Pulmonary Medicine. Read the abstract below and click here to view the complete Open Access m
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